
Case Study C
Understanding vaccine production, distribution and uptake in Ghana and Uganda
About
Our research aims to identify how stakeholders, institutions and infrastructures that previously guided national vaccine distribution and use will be impacted by a new focus on (local) manufacturing of vaccines. How will national vaccine ecosystems and distribution infrastructures be affected or integrated with new supply locations? How will existing regulatory frameworks and policies adapt to support local vaccine production? How will communities accept locally produced vaccines?
Work Packages
Vaccine Cold Chain
Vaccine Uptake And Acceptance
Health Technology Assessement (HTA)
Methods
- Interdisciplinary methods.
- Involving transdisciplinary stakeholders at each stage (see figure).
- Mixed-methods approach, combining qualitative and quantitative techniques.
- Semi-structured interviews with key informants and stakeholders, participant observation.
- Survey among stakeholders.
- Focus group discussions with health workers, patients and communities.
- Social listening and sentiment analysis.
- Discrete choice experiment, policy scenario analysis.
- Predictive modeling.
- Health Technology Assessment (HTA).
Expected Outcomes
- Increased understanding of different valuations of first and second order infrastructures and their interaction.
- Detailed understanding of dynamics of public trust in vaccines in Ghana.
- A framework of the social determinants of vaccine trust in imported versus locally produced vaccines.
- A modified HTA approach (incl. additional data sources, evaluation dimension) increasing the acceptability and quality of decision-making.
Involved Institutions





